Found 13 matching trials
The SAPPHIRE Study (Systolic And Pulse Pressure Hemodynamic Improvement By Restoring Elasticity)
PHASE2The purpose of this study is to evaluate the safety and efficacy of ALT-711...
Location
Multiple Locations
Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function
PHASE2Healthy but sedentary aging leads to increased morbidity and mortality of c...
Location
Radboud University Nijmegen Medical Centre
The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
PHASE2The purpose of this study is to test the hypothesis that treatment with ora...
Location
Wake Forest University Baptist Medical Center, Department of Cardiology
The BENEFICIAL Study: Evaluating the Efficacy and Safety of Alagebrium (ALT-711) in Patients With Chronic Heart Failure
PHASE2Several lines of evidence have suggested that Advanced Glycation End-produc...
Location
Dept. Cardiology - University Medical Center Groningen
Study of Alagebrium in Patients With Insulin-Dependent Type 1 Diabetes and Microalbuminuria
PHASE2Based upon the preclinical evidence in models of diabetic nephropathy under...
Location
Royal Prince Alfred Hospital
The Effect of Exercise and Alagebrium on the Diastolic Function of the Heart
PHASE2The purpose of this study is to determine whether an investigational drug (...
Location
The Institute for Exercise and Environmental Medicine
Systolic Pressure Efficacy and Safety Trial of Alagebrium (SPECTRA)
PHASE2This study comprises a 3- to 6-week hydrochlorothiazide run in phase, follo...
Beginning a Randomized Evaluation of the AGE Breaker Alagebrium in Diastolic Heart Failure (BREAK-DHF-I)
PHASE2This study is being done to evaluate the safety and effectiveness of alageb...
Location
Multiple Locations
STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH
PHASE2Determine whether increasing arterial distensibility by decreasing advanced...
Location
Johns Hopkins University School of Medicine
The SILVER Study: Systolic Hypertension Interaction With Left Ventricular Remodeling
PHASE2The purpose of this study is to evaluate the safety and efficacy of ALT-711...
Location
Multiple Locations